[stem-ebola] Basic Reproduction Number as Sum of Community + Hospital +

[vruslan@xxxxxxxxxxxxxx]

Hello all,

During last week's call (which was excellent), we had briefly discussed 
the basic reproduction number contributions from Community Transmission 
(RI), Hospital Transmission (RH), and Funeral Transmission (RF).  There 
was substantial interest in evaluating how these parameters might impact 
the spread of the virus.

I found the paper which discussed these values in the context of the 
2014 Ebola outbreak. . .  They are originally from the Legrand et al. 
model published in 2007, but were discussed in the Gomes et al. PLOS 
paper published Sep 2nd, 2014.

"In the Legrand et al. model [10] the basic reproductive number can be 
written as the sum of three terms relative to the transmission in the 
community, hospital and funeral settings, yielding RI = 0.8 [0.3 − 0.9], 
RH = 0.4 [0.2 − 1.4] and RF = 0.6 [0.2 − 1.0], respectively." (Gomes et 
al., 2014).

sources:

Assessing the International Spreading Risk Associated with the 2014 West 
African Ebola Outbreak (Gomes et al, 2014)

link: 
http://currents.plos.org/outbreaks/article/assessing-the-international-spreading-risk-associated-with-the-2014-west-african-ebola-outbreak/

...and the original paper which discussed these parameters...

[10] Legrand J, Grais R, Boelle P, Valleron A, Flahault A (2007) 
Understanding the dynamics of Ebola epidemics. Epidemiol Infect 135: 
610.  link:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870608/

Hope this helps.